Incidence of organophosphate and carbamate poisoning in dogs within Maiduguri, North-eastern Nigeria

The persistent application of chemicals in pest control and agricultural processes possess a public health concern as their use are often associated with acute or chronic poisoning cases in both humans and animals. In veterinary medicine, pesticides such as organophosphates and carbamates are exclusively used in ectoparasitic control through pour on, tick bath and fumigation. The incidence of organophosphate or carbamate poisoning in dogs within Maiduguri, north-eastern Nigeria was assessed using three government approved and licensed veterinary centres. Data were obtained through the review of three years (2016-2018) retrospective cases of organophosphate/carbamate poisoning and administration of questionnaires to actively practising veterinarians. Investigation revealed that organophosphate/carbamate poisoning in dogs within Maiduguri metropolis constituted 37% of poisoning cases and was on the increase in recent years with 22.96% of the total cases reported in 2016, 34.08% in 2017 and 42.96% in 2018. The case was most prevalent at the peak of the rainy season around July and August. The common clinical signs observed include salivation, vomiting, diarrhoea, muscle spasms, severe weakness and paralysis. Management was usually supportive and symptomatic while antidotal therapy revolved on atropine sulphate only. The effect of ageing in organophosphate poisoning was neglected by most of the clinicians as more than 50% would administer atropine sulphate without considering the duration of the onset of poisoning. It was concluded that the incidence of organophosphate and carbamate poisoning in dogs in Maiduguri constituted 37% of all poisoning cases where 22.96% and 42.96% of it were reported in 2016 and 2018, respectively. Enlightenment programmes for the public and professionals are recommended on the increased cases of poisoning and proper use of antidote in the treatment of chemical toxicosis

CHEMICAL COMPOSITION AND MICROBIOLOGICAL PROPERTIES OF PELLETIZED CASSAVA BASED DIETS AT DIFFERENT DAYS OF STORAGE

This study was carried out to determine storability, microbiological assay and chemical composition of pelletized cassava based diets. Four nitrogenous sources were used in the experimental diets as follows: T1, contained 200g/kg palm kernel cake (PK); 200g/kg caged layers droppings (CL) (T2), 200g/kg Gmelina arborea (GA) leaves (T3) and 40g/kg urea (UR)(T4). All the diets were pelletized. Other ingredients (g/kg) that made up each of the treatments were as follows: cassava sievate, 205; molasses, 100; Sulphur, 3; corn bran, 80; salt, 7; vit./min. Premix, 5. Media used were Salmonella Shigella agar, Potato dextrose agar, Manitol salt agar and Eosine methylene blue agar. Samples (1g) were taken at intervals of 1, 15 and 30 days for microbial analysis, while chemical composition was analysed at  1 day and 30 days after storage. Data generated were subjected to one way Analysis of Variance using Completely randomized design. No visible colour change, caking and mould growth were observed. Most of the bacteria and fungi isolated (Staphylococcus aureus, Enterobacter sp., Mucour sp., Aspergillus sp.,) were persistent throughout the storage period. There was no significant difference between microbial profile and total viable counts of the diets forms. GA had the highest level of crude protein. Proximate and fibre fractions of the diets reduced with increase in storage age. Thus, feeding animals with the pelletized cassava-based feed with urea as the non-protein nitrogen source either readily or after storage is recommended.     &nbsp

Geochemical investigations of a Portion Obu Hill Marble Deposit Okpella, Edo-State, Nigeria

The Obhu marble deposit is located at latitude 7o 21´ 31.2´´ to 7o 21´ 34.9´´ and longitude 6o 25´ 11.6´´ to 6o 25´ 18.0´´. The geochemical investigations of a portion of the Obhu hill marble deposit was aimed at investigating the reserve estimate in tonnage, rock mass/overburden volume and the geochemical composition of the deposit. This study was conducted by using vertical electrical sounding (VES) geophysical method to obtain the geo-electric parameters of the deposit, and to determine the reserve estimate of the Marble deposit of study area. The result shows that the reserve tonnage is 4.6 x 106 Tons and rock mass reserve/overburden volume ratio is 9:1.The chemical analysis were compared with the RMRDC of Nigeria for each element suitable for production of cement, fertilizer, iron, steel and other industrial uses. The MgO values of the samples 1 and 2 does not falls within the acceptable value of 6 % of RMRDC, with the exception of sample 3 which falls within the acceptable limit. CaO, Al2O3 and P2O5 values of the samples falls within the acceptable limits of RMRDC and so suggest that the marble can be put to industrial use, while the Fe2O3 content of sample 2 and 3 makes them probably not best suited for industrial use, except for sample 1 having a lower value of 1.85 %. The silica SiO2 content values for the three samples exceeded the recommended standard of RMRDC of 5 %. This result reveals that the marble deposit is suitable for most industrial use

Diversité et évaluation participative des cultivars du manioc (Manihot esculenta Crantz) au Centre Bénin

Le manioc est une plante alimentaire qui contribue fortement à la sécurité alimentaire au Bénin. Pour évaluer sa diversité variétale, les performances  agronomiques, technologiques et culinaires de ses cultivars dans la région centrale du Bénin, 41 villages ont été prospectés. Sous réserve de  synonymie, 107  cultivars de manioc ont été recensés dont 59 élites. L’indice de diversité de Shannon est de 3,78 et traduit une importante diversité variétale. Le nombre de  cultivars recensés varie de 3 à 26 par village (10 en moyenne). Dans les villages où une perte de diversité variétale est notée, son taux a varié de 6,25 à 80% avec  un taux moyen de 42,22% par village. Les cultivars à produire sont choisis sur la base de 21 critères dont les plus importants sont la forte productivité (16,37% de reponses), la qualité et le rendement en gari (15,52% de reponses) et la précocité (13,27% de reponses). Les contraintes de production (9 au total) perçues par les producteurs peuvent etre levées par l’utilisation des  cultivars performants. L’évaluation participative a révélé l’existence de très peu de cultivars performants par  rapport aux paramètres biotiques et abiotiques. La mise en place d’un programme d’amélioration et de création variétale est fortement recommandée pour la relance de la production du manioc au Bénin.Mots clés : Bénin, critère de préférence, cultivar élite, diversité variétale, évaluation participative, manioc

Toxins and adhesion factors associated with Staphylococcus aureus strains isolated from diarrhoeal patients in Benin

Staphylococcus aureus is a causative agent of acute and infectious diarrhoea. In Africa, there is no sufficient information on the virulence and the degree of factors produced by its diarrhoea-isolated strains. Clinical features and virulence factors produced by S. aureus isolated from diarrhoeal-patients admitted at the Hospital Hubert Koutoukou Maga (HKM) in Cotonou was investigated. The virulence factors were screened by radial immunoprecipitation and multiplex polymerase chain reaction (PCR).Fifteen antibiotics were tested. Among independent 115 patients examined for diarrhoea, 32 had faeces positive for S. aureus isolated as pure culture. Most of these patients were hospitalized (21/32) and developed aqueous, bloody and painful diarrhoea, after antimicrobial therapy. About 62% were resistant to oxacillin. Genes encoding for clumping factor B and for laminin binding protein were detected in 62% of S. aureus isolates. About 94% of LukE-LukD producing strains have been isolated from patientsdeveloping post-antibiotic associated diarrhoea (PAAD). The Panton-Valentine Leucocidin (PVL) was produced by 19% of isolates, all from PAAD. This study points out new data concerning virulencefactors and adhesion factor produced by S. aureus strains isolated from diarrhoea in Benin. The culture of the faeces will not always allow the diagnosis. It is important to update a technique, which enablesresearchers to carry out the virulence factors produced by these bacteria

CONSUMPTION PATTERN OF MAIZE BASED DISHES IN FOUR AGRO-ECOLOGICAL ZONES OF NIGERIA

The global picture had dramatically changed the lifestyles of Nigerian citizens pushing them into various fast-eating cultures with more instant and tasty meals, and the attendant gradual relegation of our traditional rich eating cultures. Studies were carried in eight Local Government Areas of Nigeria from the four Agro-Ecological Zones (AEZs) namely: moist savanna (Oyo State), humid forest (Lagos State), mid-altitude (Abuja) and dry Savanna (Kaduna State). Stratified multistage sampling technique with structured questionnaires from 1641 respondents and focus group discussions (FGDs) were employed to identify the maize-based dishes consumed and determined the frequency of consumption. The demographic characteristics revealed that 54.8% of the respondents were male. Residents in the rural area were more (56.8%) and majority of the respondents were between the ages of 26-45 years (67.6%), while more Christians (57.88%) participated in the study than any other religion. Results showed that thirty–two maize-based dishes were identified, of which ten were frequently consumed. Ogi was the most popular maize-based dish (73.5%) consumed in the AEZs while corn pudding was the least consumed (28.5%). There were significant differences (p<0.05) in all the sensory attributes measured. The low consumption of majority of the maize-based dishes raises concern for the current campaign on mobilizing local biodiversity which has been reported to be one of the food based intervention strategies for solving nutrition problems among population groups

Environmental Susceptibility and Resistance to Coronavirus Disease-19 (COVID-19): A Review

It is believed that certain environmental factors modulate coronavirus disease-19 (COVID-19). This review outlines the role of environmental factors in COVID-19 infectivity, spread, and severity. Relevant articles were retrieved from Google Scholar, SpringerLink, and Scopus, then pooled and duplicates removed with EndNote software. Available information reveals that temperature, relative humidity (RH), sunlight, pollutants, and population density modulate COVID-19 infectivity and pathogenicity. COVID-19 spread is promoted by low temperature (< 25 °C) and RH (< 40%), whereas it is inhibited by high temperature (> 25 °C) and RH (> 40%). Sunlight exposure alters the virus’s genetic material and boosts the host’s immune function by raising serum vitamin D (25-hydroxyvitanim D), reducing the virus’s viability and replication. Prolonged indoor stays with poor ventilation cause re-breathing of the air and increase carbon dioxide concentration, particularly in crowded rooms, predisposing to COVID-19. Pollutants, including particulate matter, nitrogen dioxide, ozone, and sulphur dioxide, may overexpress the virus’s receptor called angiotensin-converting enzyme 2 (ACE2), thereby increasing the virus’s infectivity. Pollutants may also induce inflammation of the respiratory tract, weakening the immune function and thereby increasing susceptibility to COVID-19. High population density increases body contact and thus susceptibility to the virus. To stem the incidence and mortality of COVID-19, the mentioned environmental factors must be kept at healthy levels

Decomposing the gap in missed opportunities for vaccination between poor and non-poor in sub-Saharan Africa : a multicountry analyses

Understanding the gaps in MOV between poor and non-poor in sub-Saharan Africa (SSA) would enable an understanding of factors associated with interventions for improving immunization coverage to achieving universal childhood immunization. We aimed to conduct a multicountry analyses to decompose the gap in MOV between poor and non-poor in SSA. We used cross-sectional data from 35 Demographic and Health Surveys in SSA conducted between 2007 and 2016. Descriptive statistics were used to understand the gap in MOV between the urban poor and non-poor, and across the selected covariates. Out of the 35 countries included in this analysis, 19 countries showed pro-poor inequality, five showed pro-non-poor inequality and remaining 11 countries showed no statistically significant inequality. Among the countries with statistically significant pro-illiterate inequality, the risk difference ranged from 4.2% in Congo DR to 20.1% in Kenya. The important factors responsible for the inequality varied across the countries. In Madagascar, the largest contributions to the inequality in MOV was media access followed by number of under-five children and maternal education. However, Liberia media access narrowed the inequality in MOV between poor and non-poor households.The findings indicate that in most SSA countries, children belonging to poor households are most likely to have MOV and that socio-economic inequality in missed opportunities for vaccination is determined not only by health system functions, but also by factors beyond the scope of health authorities and care delivery system. Suggesting the the importance of addressing the social determinants of health, particularly education

Rural-urban disparities in missed opportunities for vaccination in sub-Saharan Africa : a multi-country decomposition analyses

Background In this study, we aimed to explore the rural-urban disparities in the magnitude and determinants of missed opportunities for vaccination (MOV) in sub-Saharan Africa. Methods This was a cross-sectional study using nationally representative household surveys conducted between 2007 and 2017 in 35 countries across sub-Saharan Africa. The risk difference in MOV between rural or urban dwellers were calculated. Logistic regression method was used to investigate the urban-rural disparities in multivariable analyses. Then Blinder-Oaxaca method was used to decompose differences in MOV between rural and urban dwellers. Results The median number of children aged 12 to 23 months was 2113 (Min: 370, Max: 5896). There was wide variation in the the magnitude of MOV among children in rural and urban areas across the 35 countries. The magnitude of MOV in rural areas varied from 18.0% (95% CI 14.7 to 21.4) in the Gambia to 85.2% (81.2 to 88.9) in Gabon. Out of the 35 countries included in this analysis, pro-rural inequality was observed in 16 countries (i.e. MOV is prevalent among children living in rural areas) and pro-urban inequality in five countries (i.e. MOV is prevalent among children living in urban areas). The contributions of the compositional ‘explained’ and structural ‘unexplained’ components varied across the countries. However, household wealth index was the most frequently identified factor. Conclusions Variation exists in the level of missed opportunities for vaccination between rural and urban areas, with widespread pro-rural inequalities across Africa. Although several factors account for these rural-urban disparities in various countries, household wealth was the most common